In this study,the seismic performance of prefabricated reinforced concrete (RC) shear walls with circular holes and flexible cable connections is investigated,with focuses on the wall flange to web effects. Totally eight full-scale walls of typical line shape,L-shape,I-shaped type-I and I-shaped type-II are tested under quasi-static loading schemes for their failure mechanisms,characteristic loads,ductility,and shear capacity. The results show that with flexible cable connections,shear wall flanges can improve the crack resistance of the webs which specifically mitigates vertical cracking along the circular holes in the web,and shear wall flanges change the stress distribution and failure mechanism of the web which effectively improve the web’s yield and ultimate capacity of the walls. However,wall flanges have negligible effects on the yield displacement and ductility. Even though the resultant elastic story drift is small enough and meet the code requirements,flexible cable anchorage in prefabricated RC circular-hole walls still needs being optimally designed. Since circular holes can significantly reduce the in-plane shear capacity of shear wall,the experimental shear capacity is 50% lower than the code-specified shear capacity,whichshall be reflected by the current Chinese code.