Abstract: In this work, an experimental study was conducted on the seismic behavior of precast concrete column specimens before and after treatment of sleeve grouting defects. 9 precast concrete column specimens were designed, and to treat the sleeve grouting defects of precast column specimens, the method of directly refilling and the method of repairing after breaking were applied. Comparative analysis of low-frequency cyclic loading tests were carried out on the seismic behaviors, such as failure mode, hysteresis characteristics, load-carrying capacity, ductility and energy dissipation capacity, of the precast concrete column specimens before and after treatment of sleeve grouting defects. The results suggest that precast concrete column specimens exhibit two failure models, that is, failure at column bottom section and failure at the section around sleeve top. The precast concrete column specimens after treatment of sleeve grouting defects have a failure at column bottom section, which is the same as that of the intact precast column specimen. The positive peak load of the precast concrete column specimen after treatment of sleeve grouting defects is increased by 19% to 62%, the displacement at failure point is increased by 11% to 50%, and the total cumulative energy dissipation value is increased by 48% to 157%. After treatment of sleeve grouting defects, the hysteretic characteristics, load-carrying capacity, ductility and energy dissipation capacity of the precast concrete column specimens have recovered to the level of intact precast concrete column specimen. Since the method of directly refilling is simple, effective and easy to operate, it is recommended to be applied and promoted in engineering practice.